Extension of extramammary Paget disease of the vulva to the cervix

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چکیده

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Extension of extramammary Paget disease of the vulva to the cervix.

Extramammary Paget disease of the vulva was found in association with vulval adenocarcinoma in an elderly woman who also had a uterine prolapse. The characteristic histological appearances of extramammary Paget disease were masked by striking reactive changes in the squamous epithelium. Primary excision of both the intraepithelial and invasive disease appeared complete. However, a subsequent hy...

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Extramammary Paget Disease of the Vulva - Case Report.

Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae...

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BACKGROUND Extra-mammary Paget's disease of the vulva (EMPDV) is an infrequent chronic disease that often recurs. The aim of the study was to assess the presence of neoangiogenesis and the expression of epithelial-mesenchymal transition (EMT) markers in EMPDV, and their potential correlation with stromal invasion. METHODS All the women consecutively treated for EMPDV at our Institute, between...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1999

ISSN: 0021-9746

DOI: 10.1136/jcp.52.7.538